Interestingly, unlike the increase in the double positive population observed upon inhibition of Mcl-1 signaling (Fig. 2B), inhibition of the PI3K/Akt pathway increased the apoptotic population (Fig. 3C) and thereby decreased the population of viable neutrophils (Fig. 3D), suggesting that Chlamydia infection interfered with apoptotic cell death in neutrophils. Here, MCL1 is linked to chlamydia infectious disease.