P2RX1 and type 2 diabetes mellitus: To determine the common stem cell-related biomarkers for T2DM and sepsis, we first chose the top 15 genes based on functional similarity scores for the following analysis, namely, ISOC1, LBH, AMIGO2, FES, RAB13, STXBP2, KLRG1, MPO, DDAH2, CAMP, MMP9, GRAMD1A, P2RX1, CAPG, and PASK (Figure 2A).