In T2DM (Figures 4A,B) (Supplementary Table S3), both genes were significantly enriched in immune-related pathways (e.g., FcγR-mediated phagocytosis, B cell receptor signaling), infectious disease pathways (e.g., Helicobacter pylori and Leishmania infections), and growth factor signaling (VEGF/ErbB pathways), and genetic information processing (translation)-related pathways (Ribosome). The gene discussed is VEGFA; the disease is infectious disease.