CD8+ T cells in treated tumor slices displayed higher motility and high confinement within the tumors, with average speed of 10 μm min−1 and track straightness of 0.18, as compared to isotype control tumors (1.9 μm min−1 and 0.25, respectively) (Figures 1L–1N and S1C and Videos S5 and S6). The gene discussed is CD8A; the disease is neoplasm.