CDH2 and posterior cortical atrophy: To predict the probability of having an aggressive PCa, we stratified the patients based on their Gleason scores (≤3 + 4 or ≥4 + 3), and we evaluated the distribution of the clinicopathologic data and the expression of biomarkers (Phospho-Rb S249, N-cadherin, β-catenin, and E-cadherin) (Tables 3 and 4) in each category through a bivariate analysis.