Conversely, in LRG, the risk score exhibited a stronger positive correlation with IFNG expression (ρ = 0.1984, P = 0.002146), indicating a potentially enhanced anti-tumor immune response despite a higher correlation with T cell exclusion (ρ = 0.3204, P < 0.0001) (Supplementary Figure 5F). Here, IFNG is linked to neoplasm.