To further investigate the association between Scissor+ epithelial cells and the prognosis of PAAD patients, LASSO-Cox regression analysis was employed to develop a prognostic risk model, which identified seven genes: TATDN1, CAV2, CLDN1, LIPH, MT1E, PSCA, and MMP3 (Figure 4B). This evidence concerns the gene CLDN1 and pancreatic adenocarcinoma.