Specifically, It has been shown to upregulate neprilysin (NEP) expression in the hippocampus, promote Aβ degradation, reduce hippocampal Aβ burden, repair Aβ-induced neuronal damage, regulate amino acid and lipid metabolism, and mitigate neuronal injury, ultimately slowing cognitive decline (Wang et al., 2020; Wang et al., 2019). This evidence concerns the gene MME and Mental deterioration.