SLC7A11 and obesity due to melanocortin 4 receptor deficiency: Arbutin, a natural antioxidant, inhibits obesity-associated protein (FTO), which increases the m6A methylation level of SLC7A11, promotes the expression of SLC7A11, and ultimately inhibits iron death, slowing down the progression of NAFLD in vivo and in vitro (Jiang et al., 2023).