In addition, it was found that the differentially expressed genes presented the associations with oncogenic pathways (e.g., cell cycle, cellular senescence, p53, mitogen-activated protein kinases (MAPK), phosphoinositol-3 kinase (PI3K)-Akt, Ras, Ras-associated protein1 (Rap1), cyclic adenosine monophosphate (cAMP), and Forkhead box O (FoxO) signaling pathways, and pathways in cancers) (Supplementary Fig. S1F,G). The gene discussed is AKT1; the disease is cancer.