Previous studies have shown that calcium/calmodulin-dependent protein kinase II beta (CAMK2B) plays a significant role in the growth and development of neurons and synaptic plasticity; additionally, it is implicated in various neuropathological processes involving sleep disorders [10], memory disorder, severe intellectual disability [11], mental retardation [12], schizophrenia is, neurodevelopmental disorder [13,14], and Alzheimer’s disease [15]. This evidence concerns the gene CAMK2B and Intellectual disability.