Cervical cancer C33A cells in the OTUD5 overexpression group were more sensitive to radiotherapy compared with the OTUD5-silenced group and the control group because OTUD5 overexpression reduces the level of AKT phosphorylation activation through deubiquitination to increase the sensitivity of cervical cancer to radiotherapy [77]. The gene discussed is AKT1; the disease is cervical carcinoma.