IFNG and neoplasm: Studies combining Perturb-Cellular Indexing of Transcriptomes and Epitopes by Sequencing (CITE) with CRISPR-Cas9 perturbation demonstrated that impaired interferon-γ (IFN-γ) signaling in melanoma-tumor-infiltrating lymphocyte (TIL) co-cultures compromises antigen presentation, facilitating immune escape [41].