TP53 and medulloblastoma: The category medulloblastoma molecularly defined is further divided into four subtypes: (i) WNT-Activated Medulloblastomas (wingless/integrated (WNT)–activated subtype), (ii) SHH-Activated Medulloblastomas (Sonic hedgehog (SHH)–activated medulloblastomas) TP53-wildtype and (iii) SHH-Activated Medulloblastomas TP53-mutant, (iv) Non-WNT/Non-SHH Medulloblastomas [7].