These sources include clinical assessments such as the Mini-Mental State Examination (MMSE), Clinical Dementia Rating–Sum of Boxes (CDR-SB), and the Alzheimer's Disease Assessment Scale–Cognitive Subscale (ADAS-Cog), along with neuroimaging markers including hippocampal volume, cortical thickness, and standardized uptake value ratios from amyloid and tau positron emission tomography imaging. Here, MAPT is linked to Alzheimer disease.