CLEC7A and neoplasm: Typically, fungal pathogen-associated molecular patterns (PAMPs) (e.g., β-glucans) or bacterial metabolites are capable of modulating host cellular receptors (e.g., Dectin-1 for fungi versus Toll-like receptors for bacteria) and downstream signaling cascades [10], further regulating tumor biology or antitumor immunity (Fig. 1A).