CLEC7A and neoplasm: A recent study focusing on intratumor fungi in LUAD has unraveled that tumor-resident A. sydowii regulates the β-glucan/Dectin-1/CARD9 axis in macrophages to promote IL-1β-mediated expansion and activation of myeloid-derived suppressor cells, thus contributing to an immunosuppressive TME for lung cancer development [8].