No significant associations were found between specific IgE levels (Fel d 1, Fel d 2, Fel d 4; mono- or oligosensitized) and the severity of asthma, rhinitis, or atopic dermatitis, nor with the classification of asthma or rhinitis (data for Fel d 2 and Fel d 4 not shown). The gene discussed is IGHE; the disease is rhinitis.