To evaluate the potential of PRDX3 being a prognostic factor in CCa, we constructed a multivariate Cox proportional hazard model, where age, tumor size, LNM, LVSI and PRDX3 were identified as independent prognostic factors for OS in CCa patients, and tumor size, LNM, LVSI, as well as PRDX3 were confirmed as independent prognostic factors for RFS (Table 4). The gene discussed is PRDX3; the disease is neoplasm.