Additionally, protein-damaging missense variation in CXADR was linked to cervical spondylosis (P = 5.19-5, Beta = 3.88-2), FAM3D was associated with B44 aspergillosis (P = 3.35-5, Beta = 7.14-2), and POGLUT3 with xenograft replacement of aortic valve (P = 3.18-5, Beta = 4.31-2), stroke (P = 3.22-5, Beta = 1.45-2) and vascular/heart problem (P = 6.65-5, Beta = 1.31-2). This evidence concerns the gene FAM3D and stroke disorder.