Philadelphia chromosome (Ph)-like acute lymphoblastic leukemia (ALL), a subtype of acute lymphoblastic leukemia, exhibits gene expression profiles and activated kinase signaling pathways similar to those of Ph + ALL yet notably lacks the BCR-ABL1 fusion gene (Harvey and Tasian, 2020; Yadav et al., 2021; Roberts, 2017). This evidence concerns the gene ABL1 and acute lymphoblastic leukemia.