In addition, noncoding RNAs such as miR‐29a‐3p, which normally represses COL1A1 and TGFBR1, are downregulated in keloids, whereas competing lncRNAs (e.g., H19) and circRNAs (e.g., hsa_circ_0020792) sequester miRNAs to further activate TGF‐β/Smad signaling and collagen expression [46, 50, 51, 52, 53]. This evidence concerns the gene TGFB1 and keloid.