The assessment of AP is mostly indirect, relying on biomarkers such as C-reactive protein (CRP), and procalcitonin (PCT), as well as scoring systems such as the Ranson score, the Acute Physiology and Chronic Health Evaluation II (APACHE II) score, and the Bedside Index for Severity in Acute Pancreatitis (BISAP) score. This evidence concerns the gene CRP and alkaline phosphatase measurement.