CA4 and cancer: NEK2, PKMYT1, MMP11, CPA1, COL10A1, HSD17B13, CA4, MYOC, LYVE1) and addressed the ‘cancer’ vs. ‘normal’ binary classification, producing BrcaDx (https://apalania.shinyapps.io/BrcaDx) (Muthamilselvan and Palaniappan, 2023) with a balanced accuracy of 95.52% on the BRCA-KR and GTEx.