Some noteworthy features from this model include: (i) CDH1 (E-cadherin), whose germline mutations were strongly associated with lobular carcinoma (Corso et al., 2018), was found to have a specific downregulated expression signature in ILC samples; (ii) CCL14, which is known to promote angiogenesis and metastasis in breast cancer (Li et al., 2011), was found oncogenic in expression across both histological subtypes. This evidence concerns the gene CDH1 and breast carcinoma.