Some noteworthy features from this model include: (i) CDH1 (E-cadherin), whose germline mutations were strongly associated with lobular carcinoma (Corso et al., 2018), was found to have a specific downregulated expression signature in ILC samples; (ii) CCL14, which is known to promote angiogenesis and metastasis in breast cancer (Li et al., 2011), was found oncogenic in expression across both histological subtypes. The gene discussed is CDH1; the disease is breast lobular carcinoma.