Similarly, the overall mutation load among the 187 genes investigated was significantly higher in DLBCL/HGBCL‐MYC/BCL2 and DLBCL/HGBCL‐NOS than in B‐ALL (p = 2.2E−16 and p = 3.30E−06, respectively) (Figure 3B). This evidence concerns the gene BCL2 and acute lymphoblastic leukemia.