The TdT‐positive DLBCL/HGBCL‐MYC/BCL2 group was characterised by the mutation signature associated with FL (BCL2, KMT2D, CREBBP, TNFRSF14), and those associated with high‐grade transformation (MYC, TP53, CCND3, PIM1, B2M, DDX3X, S1PR2). The gene discussed is DDX3X; the disease is diffuse large B-cell lymphoma.