Since the majority of TdT‐positive DLBCL/HGBCLs originate from IGH::BCL2‐positive FL or its precursor cell population following acquisition of a MYC translocation, this raises the question of whether the aberrant TdT expression might be due to dysregulated transcriptional activity of highly expressed MYC. The gene discussed is DNTT; the disease is diffuse large B-cell lymphoma.