The most closely-related phenotype to our study showed that the liver-targeted dual ACC inhibitor firsocostat increased adiposity and hyperglycemia in mice fed a MASH diet D09100301 (Research Diets) that has a very similar nutritional composition (40% kcal fat (mostly primex trans-fat), 2% cholesterol, and 20% kcal fructose) compared to our Amylin diet [41]. Here, IAPP is linked to Hyperglycemia.