Studies show GLPs increases calmodulin (CaM), heat shock transcription factor 1 (HSF1), family with sequence similarity 3 member C (FAM3C), and p-AKT/AKT expression in T2DM mouse hepatocytes, indicating it modulates diabetic lipid metabolism via the FAM3C-HSF1-CaM pathway [235]. This evidence concerns the gene FAM3C and type 2 diabetes mellitus.