Xue et al. [236] administered GLPs (200 mg/kg, 400 mg/kg, and 800 mg/kg) to T2DM rats showed high-dose GLPs most effectively reduced blood glucose and activated antioxidant enzymes (GSH-PX, CAT, SOD), improving hemodynamic and antioxidant activity in heart tissue. The gene discussed is CAT; the disease is type 2 diabetes mellitus.