CASP3 and type 2 diabetes mellitus: A study on diabetic rats showed that in the experimental renal tissues, JQJT downregulated the expression of Bax, Caspase-3, and cytochrome c while upregulating Bcl-2; by enhancing renal anti-apoptotic activity, this prescription exerts a certain improving effect on the pathological process of T2DM [185].