TFE3 and neoplasm with perivascular epithelioid cell differentiation: In contrast, postnatal induction of SFPQ-TFE3 in all PAX8-expressing tubular cells resulted in non-epithelial renal tumors that reproduced the morphology and immunophenotype of human PEComas without PAX8 expression, underscoring the more pronounced role of SFPQ-TFE3 in driving lineage plasticity, and consistent with the high prevalence of this fusion in human PEComas3.