While the ASPSCR1-TFE3 fusion model resulted in extrarenal PEComas26, PAX8 was widely expressed in the renal tumors in this model, suggesting that these are best classified as tRCC, though quantification of PAX8 levels relative to normal kidney was not performed. Here, TFE3 is linked to renal cell carcinoma associated with Xp11.2 translocations/TFE3 gene fusions.