TFE3 and renal cell carcinoma associated with Xp11.2 translocations/TFE3 gene fusions: Taken together, these models suggest that TFE fusions are associated with a continuum of tumor histologies (from tRCC to PEComa), corresponding to a continuum of renal lineage factor downregulation, with SFPQ-TFE3 at the furthest extreme.