WNT2 and squamous cell carcinoma: Specifically, WNT2 activates the canonical WNT/β-catenin pathway involved in colorectal and hepatocellular carcinoma48WNT7B promotes angiogenesis and is linked to several squamous cell carcinomas, and WNT11 operates through non-canonical pathways (WNT/PCP and WNT/Ca2+), contributing to cell polarity and metastasis, particularly in prostate cancer12,16,49.