Specifically, 25 out of 70 patients (allelic frequency (AF): 35.7%) harbored a TP53 mutation, three of which had not been previously reported in astrocytoma patients (g.chr17:7669615delT (AF: 45% SIFT indel: neutral effect), g.chr17:7674926 C > T (rs587778719; AF: 10.6%; SIFT: tolerated; Polyphen-2: benign), and g.chr17:7674966delC (AF: 84.4%; SIFT indel: damaging). The gene discussed is TP53; the disease is astrocytoma (excluding glioblastoma).