We screened the most common SMARCAL1 cancer-associated mutations in our DNA sequencing panel, including Arg645Ser (R645S), Phe793del (del793), and Gly945fs*1 (945 fs) mutations, which have been previously described in up to 20% of TERTp-wt/IDH-wt tumors37. This evidence concerns the gene SMARCAL1 and cancer.