ALDH binding to host cGAS influences bacterial replication, infection, or host innate immune responses, we used a cutaneous infection mouse model, in which STING has been previously implicated.[35] WT and cGas‐/‐ mice were subcutaneously injected with 2x107 USA300 MRSA, and tissues were collected from day 1 to day 3 post injection to determine CFU (colony‐forming unit) as bacterial burdens and IFN‐β secretion (Figure S1G, Supporting Information). Here, CGAS is linked to infection.