Age 15 years was chosen as the cutoff for categorization as this likely represents the age during (< 15 years) and following peak insulin resistance (≥ 15 years) [20, 21], If true, this would suggest an even more aggressive disease process in youth diagnosed with type 2 diabetes in early adolescence and perhaps a need for additional interventions to prevent future diabetes‐related complications. The gene discussed is INS; the disease is type 2 diabetes mellitus.