She suffers from hypertension, DM II, hypercholesterolemia, osteoporosis with persistent low back pain, gait instability, mixed urinary incontinence, a Body Mass Index (BMI) of 32, INICIARE of 80 [45], and GDS 2 according to the Reisberg Global Deterioration Scale [46], with a prescription of more than 9 drugs including insulin. The gene discussed is INS; the disease is familial hypercholesterolemia.