These include genes associated with pulmonary alveolar proteinosis (MARS1, CSF2RA, CSF2RB, OAS1 and GATA2), autoinflammatory disorders (STING1 and COPA) and other complex syndromes (TBX4, FARSA, FARSB and FLNA) [6, 8]. Here, MARS1 is linked to pulmonary alveolar proteinosis.