The qRT-PCR results showed that, compared with controls, Gstm1 and Igfbp6 were significantly upregulated in ARDS patients, whereas F3, Lgals1, Mgp, Tgm2, Ankrd1, and Anxa1 were significantly downregulated (Figure 6A). The gene discussed is IGFBP6; the disease is acute respiratory distress syndrome.