Several studies have shown that IL-6 is elevated in the CSF of patients with anti-NMDAR encephalitis but not in anti-LGI1 encephalitis, often accompanied by increased IL-17A and CXCL13, suggesting a subtype-specific pattern of Th17-driven inflammation (32, 34, 76, 77). The gene discussed is CXCL13; the disease is viral encephalitis.