TARDBP and amyotrophic lateral sclerosis: Ease of creating transgenic lines and using well established behavioral assays allow assessments of the neurotoxic impacts and physiological changes related to expression of the ALS-associated protein TDP-43 (Ash et al., 2010; Chen et al., 2024; Koopman et al., 2023; Van Pelt & Truttmann, 2020; Zhang et al., 2011, 2012).