TB: negativeVaricella: NegativeHepatitis: NegativeImmunological: IgA, IgG, IgM within normal limit, cytokines panel and T cell subsets within normal limitRheum: ANA NegativeMetabolic: Urine porphyria Negative, MMA level, Homocysteine level, folate and vitamin levels within normal limit. The gene discussed is CD40LG; the disease is porphyria.