Our data showed no significant differences in the aspects of female age, male age, BMI, basal FSH, Basal E2, infertile time, total Gn dosage, stimulation duration, the number of oocytes retrieved and the mean number of embryos transferred between conventional ICSI and early R-ICSI groups (p> 0.05) (Table 1). Here, BRD2 is linked to Infertility.