In patients with PCOS, there was a significant positive correlation between MAP and year, BMI, WC, HC, WHR, hirsutism score, acanthosis nigricans score, FBG, FINS, HOMA-IR, LDL, TG, TC, ApoB, ApoB/ApoA1 ratio, and FAI (P < 0.01 for all), while there was a significant inverse relationship between MAP and QUICKI, HDL, SHBG, LH, and LH/FSH ratio (P < 0.05 for all). Here, PLOD1 is linked to acanthosis nigricans.