Notably, 65-95% of PCOS patients manifested IR with compensatory hyperinsulinemia (2), and those with concurrent IR exhibit atherogenic dyslipidemia characterized by elevated TG, LDL, ApoB, TG/HDL, and ApoB/ApoA ratio, with TG and ApoB levels exhibiting positive correlation with BMI (30). The gene discussed is APOA1; the disease is metabolic syndrome.