After adjusting for age and BMI, the associations between MAP and the following parameters were notably attenuated, including HC, acanthosis nigricans score, FINS, HOMA-IR, QUICKI, HDL, TT, SHBG, FAI, LH, LH/FSH ratio, and AMH (as shown in Table 2). The gene discussed is PLOD1; the disease is acanthosis nigricans.