Patients with the highest TyG index tended to be younger, less likely to be male, and to have higher proportion of diabetes mellitus, hypertension, dyslipidemia, and higher levels of TC, high-sensitive C-reactive protein (hs-CRP), glycated hemoglobin c (HbA1c), in comparison with the other two groups (all P<0.001). The gene discussed is CRP; the disease is diabetes mellitus.