MAPT and early-onset autosomal dominant Alzheimer disease: We aimed to quantify associations of the cell-weighted Alzheimer’s disease genetic risk factors with the distinct Alzheimer’s disease endophenotype (Aβ, tau and cognitive measure) using six different cell types [astrocytes, excitatory neurons, inhibitory neurons, microglia, oligodendrocyte precursor cells (OPC) and oligodendrocytes].