Several glutamine transporters have been confirmed to be widely upregulated in cancer and are associated with tumor invasion and metastasis, such as SLC1A5 (ASCT2), SLC7A5 (LAT1), and SLC6A14 (van Geldermalsen et al., 2016; Wu et al., 2018; Wang et al., 2013). This evidence concerns the gene SLC1A5 and neoplasm.