Specifically, COL1A1 was found to be highly expressed in 13 tumor types, including breast invasive carcinoma (BRCA), diffuse large B-cell lymphoma (DLBC), esophageal carcinoma (ESCA), glioblastoma multiforme (GBM), head and neck squamous cell carcinoma (HNSC), kidney chromophobe (KICH), liver hepatocellular carcinoma (LIHC), lung adenocarcinoma (LUAD), lung squamous cell carcinoma (LUSC), pancreatic adenocarcinoma (PAAD), stomach adenocarcinoma (STAD), thyroid carcinoma (THCA), and thymoma (THYM). The gene discussed is COL1A1; the disease is carcinoma of esophagus.