The results showed that in MM cell lines (U266 and RPMI8226), the expression levels of ATIC and VAMP7 were significantly higher in the MM group compared to the control group, while the expression levels of CDKN1A, DNAJB9, EDEM1, GABARAPL1, and RAB1A were significantly lower than those in the control group (Figure 9A). This evidence concerns the gene EDEM1 and Miyoshi myopathy.