INS and type 1 diabetes mellitus: In contrast, a smaller study (n = 94) in T1D pairing CGM and connected insulin pen data found small reductions in level 1 TBR 54–69 mg/dL (3.0–3.8 mmol/L) after initiation of connected insulin pen therapy, and a significant reduction in level 2 TBR <54 mg/dL (<3.0 mmol/L).21