Comparisons among the healthy, MetS+ HTN+ ALT–, and MetS+ HTN+ ALT+ groups showed a slight elevation of serum SDC1 in the MetS+ HTN+ ALT+ group (16.32 ± 9.35 ng/mL) compared with the healthy group (15.20 ± 4.36 ng/mL) and the MetS+ HTN+ ALT– group (14.13 ± 5.23 ng/mL), although this difference was not statistically significant (p = 0.474). This evidence concerns the gene SDC1 and metabolic syndrome.