When we evaluated the association between pCR and clinicopathological features (ethnicity, race, menopausal status, nuclear grade, metaplastic subtype, Ki67, PD-L1 [CPS], stromal tumor-infiltrating lymphocyte (sTIL), tumor mutational burden and homologous recombination deficiency-related genes), the only factor significantly associated with pCR was the presence of high stromal sTILs ( ≥ 60%) (p = 0.041); PD-L1 expression was not associated with pCR. This evidence concerns the gene CD274 and neoplasm.