RECQL4 and posterior cortical atrophy: While three PPVs, RAD50 p.Glu723fs (known to PCa), TRRAP p.Ala505fs and the inframe deletion identified in RECQL4, presented in a single East African (EAC MAF = 0.0116279), the latter including a single Southern African (SAC MAF = 0.0102041), none were excluded from further analyses (Table 1).