Providing insights for possible African-relevant PCa GT candidate genes, it is notable that although a recent DDR-targeted study of 17,000 European PCa patients advocated for the inclusion of XRCC2, MRE11, POLK, POLH, and MSH59, only MRE11 (4.5 ranking) was identified in our study. This evidence concerns the gene POLH and posterior cortical atrophy.