Additional unknown candidate genes outranking FANCA include known DDR genes ERCC2, RECQL4, CLSPN, MSH3, FANCD2, HERC2, TRRAP and CREBBP (PSLP driven), DDR-relevant genes ROS1, ASPM, KMT2D, ERBB3, PRDM2, FGFR4, KMT2C, LEF1 and PER1, and the PCa germline associated oncogene RET (Supplementary Data 10). This evidence concerns the gene PER1 and posterior cortical atrophy.