RAB32 and oculocutaneous albinism type 7: We demonstrate that LRMDA coupling to Commander is essential for the RAB32-dependent biogenesis of melanosomes and show that LRMDA mutations, causative for oculocutaneous albinism type 7 (OCA7), a hypopigmentation disorder accompanied by poor visual acuity18, uncouple RAB32 and Commander binding thus establishing the mechanistic basis of this disease.