Increased FWF has been documented in older adults with AlzD (Dumont et al., 2019; Ji et al., 2017), a neurodegenerative condition associated with early onset in DS, purportedly due to the triplicated amyloid precursor protein on chromosome 21 (Bazydlo et al., 2021; Rubenstein et al., 2024; Salehi et al., 2015). This evidence concerns the gene APP and Dravet syndrome.