INS and neurodegenerative disease: The role of lactate as a glucose‐sparing energy substate may have potential relevance for populations with impaired glucose metabolism, such as individuals with brain injury (Vespa et al., 2025), neurodegenerative diseases (Goyal et al., 2023) or insulin resistance (Willette et al., 2015), where enhanced lactate metabolism may serve as a neuroprotective mechanism (Berthet et al., 2009; Patet et al., 2016; Won et al., 2012).